using nav designer for left hand items

after I make changes via the nav designer, what do i have to do to have the changes take affect?
I am attempting to use the nav designer to control who gets to use some of the items in system setup. I have assigned a role to the items of sys admin if i don't want the user to see it and I have added a product manager role to the user and assigned it to item I want them to see. It doesn't seem to lock the user out of the sys admin items. has anybody tried this?

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Select your preferred way to display the comments and click "Save settings" to activate your changes.

Come back to it tomorrow?

I've noticed that sometimes when I change a nav item, the change does not take effect immediately. I'm not sure what all is at play here--some delay between saving the change and having it actually published to the site, perhaps? Or maybe I had both the Casual View and iMIS Desktop open at the same time? Yet, when I give up and move on to something else, I find that I can come back to it and see that the change has happened. Maybe you should restart the ASI Publishing server?
Ted Ericson. ASI/Product Management